Adrianne Wilson - Poe
 

PHD. INSTRUCTOR

I study the molecular mechanisms of opioid/cannabinoid drug interactions, and the cellular adaptations that occur during chronic pain. I am focused on translational neuroscience, using rodent models of pain-depressed behavior that more closely reflect the human experience of spontaneous pain. I aim to bridge the gap between preclinical cannabinoid research and clinical cannabis medicine by launching my independent laboratory in the summer of 2019.

 
Moron Lab
Nicolas Massaly

PHD. INSTRUCTOR

 

My current work focus on the accumbal dynorphin-KOR system and how its plasticity in the presence of pain alters motivation for rewards and negative affects. Characterization of pain-induced changes in this neural circuit is critical to overcome alterations in mood, reinforcement and opioid misuse epidemic.

This focus is a direct follow up on my PhD studies on neuroplastic changes in the nucleus accumbens during opioid-induced behaviors in Bernard Frances laboratory (Toulouse, France) and first post-doctoral experience in Christoph Stein laboratory studying pain and peripheral opioid analgesia (Berlin, Germany). 

Outside of lab I love cooking, tasting new beers, listening to music, going to shows and traveling. 

 
Moron Lab
Sidney Williams

PHD. POST DOCTORAL FELLOW

 

My current work focuses on combining a novel virtual reality behavioral paradigm with two-photon imaging to observe neural networks in real time allowing for unprecedented spatio-temporal resolution while observing the structural changes that accompany drug-induced contextual memory formation.

My interest in the neurobiology of addiction began while working in Judy Grisel’s laboratory at Furman University trying to understand how endogenous levels of beta-endorphin affect alcohol consumption and continued at Florida Atlantic University in Robert Stackman’s laboratory determining the role of the head-direction cells in the anterior thalamic nuclei (ATN) in directional navigation. My doctorate work was focused on using whole-cell patch clamp methods to understand how HCN channels modulate neuronal excitability and cortical network activity in John Hablitz’s laboratory at University of Alabama, Birmingham.

 
Moron Lab
Khairunisa Ibrahim

PHD. POST DOCTORAL FELLOW

 

I first entered the pain research field in my final undergraduate year when I did Honours’ project under Dr. Sanjay Khanna at National University of Singapore. It was then that my interest in the subject developed and I embarked on my PhD journey in the same lab. My PhD work looked at the role of AMPA receptor-mediated glutamatergic network in the medial septum (MS), in modulating the hippocampal theta wave activity. The project was further developed to understand how perturbing the AMPA receptors in the MS modulates both the acute pain and chronic pain using the formalin test and chronic constriction injury model, respectively.

 
 

Moving forward in Dr. Jose Moron-Concepcion’s lab, I will start out with a longitudinal study looking at the changes in the excitability of the hippocampus in the presence of chronic pain using various models and how that might affect its connections with the nucleus accumbens, which is important in the reward system. This is in hope that it will provide some insights on how chronic pain-induced changes in the hippocampal might influence or alter drug addiction.

Outside of the lab, I love spending time with my family, exploring new places, baking and having some quiet time to read a good novel.

 
Moron Lab